A Two-Stage Allocation Scheme for Delay-Sensitive Services in Dense Vehicular Networks

Driven by the rapid development of wireless communication system, more and more vehicular services can be efficiently supported via vehicle-to-everything (V2X) communications. In order to allocate radio resource with the reasonable implementation complexity in dense urban intersection, a two-stage allocation algorithm is proposed in this paper, whose main objective is to minimize delay and ensure reliability. In particular, as for the first stage, the allocation policy is based on traffic density information (TDI), which is different from utilizing channel state information (CSI) and queue state information (QSI) in the second stage. Moreover, in order to reflect the influence of TDI on delay, a macroscopic vehicular mobility model is employed in this paper. Simulation results show that the proposed algorithm can acquire an asymptotically optimal performance with the acceptable complexity

The Relationship Between Copper Homeostasis and Lipid Metabolism

Copper (Cu) is an essential micronutrient for most living organisms. Recently, the new role of Cu in lipid metabolism has emerged. The loss of Cu homeostasis has been linked to metabolic diseases, and both Cu deficiency and Cu overload have been shown to affect lipid levels. The main goal of the studies described in this Thesis was to better understand the relationship between Cu and lipid metabolism at the cellular and the whole organism levels. Towards this goal, we first examined whether the tissue Cu status is changing in obesity. We found that Cu levels are elevated in circulation, adipose and liver tissue of obese patients and positively correlate with the body mass index (BMI), leptin and insulin. Activity of semicarbazide-sensitive amine oxidase (SSAO), the main Cu containing enzyme in adipose tissue, is higher in obese individuals and correlated with BMI. To better understand the molecular link between Cu and adiposity we identified the pathways involved in Cu action in adipocytes. For these studies, we used 3T3-L1 adipocyte cells and examined the utilization and requirements Cu during adipocyte differentiation. We found that Cu uptake increases during adipogenesis Limiting Cu during adipogenesis induces adipocyte hypertrophy. We hypothesized that the abundant Cu-containing enzyme SSAO could be involved in Cu related adipocyte hypertrophy. We demonstrate that SSAO activity depends on the organism’ Cu status. Downregulation of ATP7A, which delivers Cu into secretory pathway, reduces SSAO activity and induces adipocyte expansion. SSAO-/- cells generated using the CRISPR/Cas9 system differentiate into bigger adipocytes with increased triglyceride levels. This phenotype can be rescued by treatment of cells with a recombinant soluble SSAO during differentiation. To identify the SSAO-dependent cellular pathways, quantitative mass-spectrometry was used to analyze the proteome of adipocytes with and without SSAO. Glycolysis and lipogenesis from glucose are downregulated in SSAO-/- cells, however, proteins regulating triglyceride or ceramide /sphingomyelin synthesis are elevated. We further confirm that glucose uptake and long-chain fatty acid are reversely regulated in SSAO-/- cells, suggesting the new mechanism of SSAO in balancing metabolic fuel selection. In conclusion, our study show that Cu regulate fat storage and energy fuel selection through mediating Cu-dependent SSAO

Digital Twin-Driven Network Architecture for Video Streaming

Digital twin (DT) is revolutionizing the emerging video streaming services through tailored network management. By integrating diverse advanced communication technologies, DTs are promised to construct a holistic virtualized network for better network management performance. To this end, we develop a DT-driven network architecture for video streaming (DTN4VS) to enable network virtualization and tailored network management. With the architecture, various types of DTs can characterize physical entities' status, separate the network management functions from the network controller, and empower the functions with emulated data and tailored strategies. To further enhance network management performance, three potential approaches are proposed, i.e., domain data exploitation, performance evaluation, and adaptive DT model update. We present a case study pertaining to DT-assisted network slicing for short video streaming, followed by some open research issues for DTN4VS.Comment: 8 pages, 5 figures, submitted to IEEE Network Magazin

“Reporting or Interpreting?”—A Discoursal Study of Broadcasts on NBA Games in China

From the perspective of empirical discourse analysis, this paper identifies the site broadcasters’ roles and cognitive blending process in NBA (National Basketball Association) broadcasts in China. The authors find that NBA broadcasters chiefly interpret the information they have obtained from sports sites and interviews with the coaches and players, employing various interpreting strategies, such as commentary, amplification, supplementation and restructure. Cognitively, the language that NBA broadcasters applied reveals their cognitive blending process of interpreting techniques, strategies, sports knowledge and attitudes towards the games, of who take up different roles to fulfill different communicating purposes, all of which project various cognitions on NBA games. Despite the fact that one role might make certain linguistic behaviors prevail over the others, especially their interpreting role, NBA site broadcasters coordinate it with other roles properly through which they present different levels of translational and constructional schematicity, thus yielding a coherent and constructional working mode of NBA broadcasting practice in China